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. 2020 Apr 7;12(4):234. doi: 10.3390/toxins12040234

Figure 1.

Figure 1

Protein-bound uremic plasma concentrations stratified for renal creatinine clearance categories at baseline. Cp, plasma concentration; HA, hippuric acid; IAA, indole-3-acetic acid; IS, indoxyl sulfate; KA, kynurenic acid; KYN, kynurenine; pCG, p-cresyl glucuronide; pCS, p-cresyl sulfate. One-way ANOVA with Tukey’s honestly significant difference post hoc test. The natural logarithm of hippuric acid, p-cresyl sulfate, p-cresyl glucuronide and indole-3-acetic acid was used for analysis. (A): * p = 0.036 vs. 2.5-6.4 mL/min; † p = 0.002 vs. 0 mL/min; ‡ p = 0.007 vs. 0 mL/min; § p = 0.022 vs. 0 mL/min. (B): * p = 0.023 vs. 2.5-6.4 mL/min; † p = 0.013 vs. 0 mL/min; ‡ p = 0.003 vs. 6.4 mL/min; § p = 0.007 vs. 6.4 mL/min; ∞ p < 0.001 vs. 0 mL/min.