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Postulated mechanism of disease resistance in cattle to PPRV—Schematic representation of roles of differentially expressed genes. The TLR7 mediated differential induction of RIG-I, DHX58, RLR and MDA5 contributes to the differential interferon levels which in turn modulate the viral replication across these two species. The increased levels of PDE12 might contribute to negative regulator of the OAS pathway in goats.
