Table 3.
Effects of SA-03 on biochemical parameters.
| Parameter | Vehicle | SA-03-1X | SA-03-2X | SA-03-5X | Trend Analysis |
|---|---|---|---|---|---|
| AST (U/L) | 67 ± 9 | 69 ± 6 | 67 ± 9 | 67 ± 9 | 0.7926 |
| ALT (U/L) | 36 ± 8 | 34 ± 9 | 34 ± 8 | 30 ± 6 | 0.0367 |
| CK (U/L) | 162 ± 30 | 165 ± 24 | 159 ± 16 | 162 ± 22 | 0.3890 |
| GLU (mg/dL) | 186 ± 14 | 186 ± 11 | 187 ± 14 | 187 ± 15 | 0.8841 |
| CREA (mg/dL) | 0.41 ± 0.02 | 0.42 ± 0.03 | 0.42 ± 0.02 | 0.42 ± 0.03 | 0.3146 |
| BUN (mg/dL) | 21.4 ± 3.0 | 21.4 ± 2.0 | 21.1 ± 1.9 | 21.3 ± 1.8 | 0.9156 |
| UA (mg/dL) | 1.7 ± 0.2 | 1.7 ± 0.2 | 1.7 ± 0.2 | 1.7 ± 0.3 | 0.9649 |
| TC (mg/dL) | 147 ± 22 | 147 ± 20 | 147 ± 16 | 147 ± 16 | 0.9617 |
| TG (mg/dL) | 156 ± 22 | 156 ± 19 | 156 ± 21 | 154 ± 21 | 0.7516 |
| ALB (g/dL) | 3.0 ± 0.1 | 3.0 ± 0.3 | 3.0 ± 0.3 | 3.0 ± 0.2 | 0.9723 |
| TP (g/dL) | 5.6 ± 0.3 | 5.7 ± 0.4 | 5.7 ± 0.3 | 5.6 ± 0.3 | 0.9616 |
Data are expressed as mean ± SD (n = 10 mice per group). AST, aspartate aminotransferase; ALT, alanine transaminase; CK, creatine kinase; GLU, glucose; CREA, creatinine; BUN, blood urea nitrogen; UA, uric acid; TC, total cholesterol; TG, triacylglycerol; ALB, albumin; TP, total protein.