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. 2020 May 8;11:357. doi: 10.3389/fgene.2020.00357

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Copyright © 2020 Deng, Li, Wang, Geng, Cai, Tang, Wang, Yu, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Downregulation of circ_0001946 inhibits the epithelial–mesenchymal transition (EMT) pathway in colorectal cancer (CRC) cells. (A) Expression of an epithelial marker (E-cadherin) and a mesenchymal marker (N-cadherin and vimentin) in LoVo cells (upper panel) and the representative gray value of LoVo cells (lower panel) after transfection with circ_0001946-specific siRNAs. (B) Expression of an epithelial marker (E-cadherin) and a mesenchymal marker (N-cadherin and vimentin) in SW480 cells (upper panel) and the representative gray value of SW480 cells (lower panel) after transfection with circ_0001946-specific siRNAs. All experiments were repeated at least three times. ***P < 0.001.