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. 2020 May 7;14:389. doi: 10.3389/fnins.2020.00389

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Copyright © 2020 Di Pino, Romano, Spaccasassi, Mioli, D’Alonzo, Sacchetti, Guglielmelli, Zollo, Di Lazzaro, Denaro and Maravita.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of training on RT/Distance curves (quadratic fitting function) in the VTI experiment, when the participant was tested with the healthy right limb (green) and with the more trained prosthesis (red) in the PRE session (lighter colors) and in the POST_NI session (darker colors). Somatosensory stimulation was always delivered non-invasively. Values are means (dots) ± SEM (bars). The healthy hand underwent a general speeding of RTs for all the tested distances yet maintaining a similar RT/Distance pattern, while the prosthesis changed the pattern of the RT/distance with a decrease of RTs in far space. This suggests an extension of the PPS induced by the embodiment of the prosthesis.