Table 1.
Patient and Primary Tumor Characteristics
| Characteristic | No. of patients (%) |
|||
|---|---|---|---|---|
| Whole cohort (n = 65) | Observation (n = 25) | Nonsurgical (n = 13) | Surgery (n = 27) | |
| Median age | 42 (16–82) years | 38 (16–76) years | 58 (20–82) years | 50 (25–67) years |
| <55 years | 48 (73.8) | 22 (88.0) | 6 (46.2) | 20 (74.1) |
| ≥55 years | 17 (26.2) | 3 (12.0) | 7 (53.8) | 7 (25.9) |
| Sex | ||||
| Female | 38 (58.5) | 17 (68.0) | 6 (46.2) | 15 (55.6) |
| Male | 27 (41.5) | 8 (32.0) | 7 (53.8) | 12 (44.4) |
| Pathological T stage | ||||
| T1 | 16 (24.6) | 7 (18.0) | 2 (15.4) | 7 (25.9) |
| T2 | 15 (23.1) | 6 (24.0) | 2 (15.4) | 7 (25.9) |
| T3 | 12 (18.5) | 4 (16.0) | 3 (23.1) | 5 (18.5) |
| T4 | 13 (20.0) | 6 (24.0) | 4 (30.8) | 3 (11.1) |
| Unknown | 9 (13.8) | 2 (8.0) | 2 (15.4) | 5 (18.5) |
| Pathological N stage | ||||
| N0 | 5 (7.7) | 3 (12.0) | 0 | 2 (7.4) |
| N1a | 17 (26.2) | 8 (32.0) | 1 (7.7) | 8 (29.6) |
| N1b | 39 (60.0) | 13 (52.0) | 10 (76.9) | 16 (59.3) |
| Unknown | 4 (6.2) | 1 (4.0) | 2 (15.4) | 1 (3.7) |
| M Stage | ||||
| M0 | 61 (93.8) | 24 (96.0) | 11 (84.6) | 26 (96.3) |
| M1 | 1 (1.5) | 0 | 0 | 1 (3.7) |
| Unknown | 3 (4.6) | 1 (4.0) | 2 (15.4) | 0 |
| Extrathyroidal extension | ||||
| Macroscopic | 16 (24.6) | 6 (24.0) | 5 (38.5) | 5 (18.5) |
| Microscopic | 29 (44.6) | 12 (48.0) | 6 (46.2) | 11 (40.7) |
| Not identified | 8 (12.3) | 3 (12.0) | 0 | 5 (18.5) |
| Unknown | 12 (18.5) | 4 (16.0) | 2 (15.4) | 6 (22.2) |
| Initial histology | ||||
| Papillary | 55 (84.6) | 23 (92.0) | 8 (61.5) | 24 (88.9) |
| Poorly differentiated | 7 (10.8) | 1 (4.0) | 4 (30.8) | 2 (7.4) |
| Hürthle cell | 3 (4.6) | 1 (4.0) | 1 (7.7) | 1 (3.7) |
| Neck dissection at initial surgery | ||||
| None | 13 (20.0) | 7 (28.0) | 0 | 6 (22.2) |
| Central | 10 (15.4) | 4 (16.0) | 1 (7.7) | 5 (18.5) |
| Lateral | 15 (23.1) | 6 (24.0) | 4 (30.8) | 5 (18.5) |
| Central and lateral | 26 (40.0) | 8 (32.0) | 7 (53.8) | 11 (40.7) |
| Unknown | 1 (1.5) | 0 | 1 (7.7) | 0 |
| Median maximum LN diameter | 2.9 (0.4–5.2) cm | 2.5 (0.4–5.2) cm | 2.6 (2.3–3.6) cm | 3.4 (0.7–5.0) cm |
| ATA risk | ||||
| Low | 0 | 0 | 0 | 0 |
| Intermediate | 22 (33.8) | 12 (48.0) | 5 (38.5) | 5 (18.5) |
| High | 28 (43.1) | 10 (40.0) | 3 (23.1) | 15 (55.6) |
| Unknown | 8 (12.3) | 2 (8.0) | 1 (7.7) | 5 (18.5) |
| Not applicable | 7 (10.8) | 1 (4.0) | 4 (30.8) | 2 (7.4) |
| AJCC stage | ||||
| I | 47 (72.3) | 21 (84.0) | 5 (38.5) | 21 (77.8) |
| II | 8 (12.3) | 2 (8.0) | 3 (23.1) | 3 (11.1) |
| III | 3 (4.6) | 1 (4.0) | 1 (7.7) | 1 (3.7) |
| IV | 3 (4.6) | 0 (0.0) | 2 (15.4) | 1 (3.7) |
| Unknown | 4 (6.2) | 1 (4.0) | 2 (15.4) | 1 (3.7) |