Table 1.
The Main Features of the Patients with Systemic Sclerosis and Healthy Control Participants
| Trait | Patients with SSc | Healthy controls |
|---|---|---|
| Number | 41 | 164 |
| Sex (female: male) | (36:5) | (144:20) |
| Age (years, mean ± SD)a | 60.10 ± 12.97 | 61.70 ± 11.56 |
| Age of onset (years, mean ± SD) | 49.05 ± 13.80 | — |
| Subtype | — | |
| lcSSc, n (%) | 20 (48.78) | — |
| dcSSc, n (%) | 21 (51.22) | — |
| Autoantibodies | — | |
| ANA+, n (%) | 39 (95.12) | — |
| ATA+, n (%) | 14 (34.15)b | — |
| ACA+, n (%) | 21 (51.22)c | — |
| Raynaud's phenomenon (%) | 41 (100) | — |
| Smoking | — | |
| Current smoker n (%) | 6 (14.63) | — |
| Past smoker n (%) | 8 (19.51) | — |
| Never n (%) | 27 (65.85) | — |
a
p = 0.47 (patients age vs. control age).
b
13 (92.86%) out of 14 patients with dcSSc.
c
18 (85.71%) out of 21 patients with lcSSc.
ACA, anticentromere autoantibodies; ANA, antinuclear autoantibodies; ATA, antitopoisomerase autoantibodies; dcSSc, diffused cutaneous scleroderma; lcSSc, limited cutaneous scleroderma; SD, standard deviation.