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Tetrandrine treatment attenuated DOX-related cardiac injury in mice. (a) Body weight of animals in the indicated groups (n = 12). (b) The ratio of heart weight to tibial length (n = 12). (c–e) The levels of cTnI, NT-proBNP, and LDH in the indicated groups (n = 6). (f) The mRNA levels of BNP in mice (n = 6). ∗P < 0.05 compared with the NS group. #P < 0.05 compared with mice after DOX injection.
