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Tetrandrine did not provide cardiac protection in Nrf2-deficient mice. (a) Nrf2 protein expression (n = 6). (b) EF (n = 9). (c) The levels of cTnI (n = 6). (d) Myocardial 4-HNE levels (n = 6). (e) Caspase3 activity after Nrf2 deficiency (n = 6). ∗P < 0.05 vs. the matched control.
