Table 1.

Results of the literature review with the set of criteria and filters.

	Type of manuscript	Molecule/s∗	Dog/cat	References
1	Review	—	Dog	Vandeweerd et al., 2013 [10]
2		—	Dog/cat	Webster and Cooper, 2009 [11]
3		—	Dog	Honeckman, 2003 [2]
4	Research paper	Silybum marianum	Dog	Sgorlon et al., 2016 [12]
5		S-Adenosylmethionine and silybin-phosphatidylcholine complex	Dog	Skorupski et al., 2011 [13]
6		Silymarin	Cat	Avizeh et al., 2010 [14]
7		S-Adenosylmethionine	Dog	Center et al., 2005b [15]
8		S-Adenosylmethionine	Cat	Webb et al., 2003 [16]
9		Silibinin	Dog	Vogel et al., 1984 [17]
10		Silymarin	Dog	Floersheim et al., 1978 [18]
11		Silymarin	Dog (and other animals)	Desplaces et al., 1975 [19]
12	Study on cell cultures	S-Adenosylmethionine and silybin	Dog	Au et al., 2013 [20]
13		Silibinin	Dog	Magdalan et al., 2009 [21]
14		Silybin; silybin-phosphatidylcholine complex	Dog	Au et al., 2010 [22]
15	Case report	S-Adenosylmethionine and silybin	Cat	Thompson, 2019 [23]
16		S-Adenosylmethionine	Dog	Schmid and Hovda, 2016 [24]
17		S-Adenosylmethionine and silybin	Dog	Bautista et al., 2015 [25]
18		S-Adenosylmethionine	Dog	Wallace et al., 2002 [26]

^∗Only those molecules satisfying our search criteria are reported in the table. Other molecules such as, for example, ursodeoxycholic acid and N-acetylcysteine, included in some manuscripts reported in the references section and listed above but that did not meet search criteria or were studied for different diseases/conditions, were excluded from the table.