Table 2.
Subgroup analysis stratified by population, sample, and publication year.
| Category | No. of studies | SEN (95% CI) | SPE (95% CI) | NLR (95% CI) | PLR (95% CI) | DOR (95% CI) | AUC (95% CI) |
|---|---|---|---|---|---|---|---|
| Population | |||||||
| Asian | 7 | 78% (71%-84%) | 68% (54%-80%) | 0.32 (0.21-0.47) | 2.5 (1.6-3.9) | 8 (4-17) | 0.81 (0.77-0.84) |
| Sample | |||||||
| >100 | 7 | 78% (70%-84%) | 66% (55%-75%) | 0.33 (0.23-0.49) | 2.3 (1.6-3.2) | 7 (4-13) | 0.80 (0.76-0.83) |
| Publication year | |||||||
| >2015 | 8 | 78% (70%-84%) | 0.69 (0.58-0.79) | 0.32 (0.23-0.46) | 2.5 (1.8-3.6) | 8 (4-15) | 0.81 (0.77-0.84) |
| Overall | 10 | 79% (73%-84%) | 0.71 (0.59-0.80) | 0.30 (0.21-0.41) | 2.7 (1.8-4.0) | 9 (5-18) | 0.82 (0.78-0.85) |
| Outliers excluded | 9 | 81% (76%-85%) | 0.72 (0.60-0.82) | 0.26 (0.20-0.34) | 2.9 (2.0-4.4) | 11 (6-21) | 0.82 (0.79-0.85) |
SEN: sensitivity; SPE: specificity; NLR: negative likelihood ratio; PLR: positive likelihood ratio; DOR: diagnostic odds ratio; AUC: area under the receiver operating characteristic curve.