Table 3.
Comparison of the predicted results for TGEV and PEDV with those annotated by NCBIa
| Number | Genome | Location (bp) |
Location (aa) |
Length (aa) | Cleavable peptide | Feature | ||
| Start | Stop | Start | Stop | |||||
| 1 | TGEV | 315 | 638 | 1 | 108 | 108 | – | PCP CP1 |
| NC_002306 | 639 | 2 951 | 109 | 879 | 771 | KIARTG|RGAIYV | PCP CP2 | |
| 2 952 | 7 478 | 880 | 2 388 | 1 509 | YNKMGG|GDKTVS | PCP CP3 | ||
| 7 479 | 8 948 | 2 389 | 2 878 | 490 | VSPKSG|SGFFDV | PCP CP4 | ||
| 8 949 | 9 854 | 2 879 | 3 180 | 302 | STLQ|SGLR | nsp2 | ||
| 9 855 | 10 736 | 3 181 | 3 474 | 294 | VNLQ|AGKV | nsp3 | ||
| 10 737 | 10 985 | 3 475 | 3 557 | 83 | STVQ|SKLT | nsp4 | ||
| 10 986 | 11 570 | 3 558 | 3 752 | 195 | TILQ|SVAS | nsp5 | ||
| 11 571 | 11 903 | 3 753 | 3 863 | 111 | TKLQ|NNEI | nsp6 | ||
| 11 904 | 12 308 | 3 864 | 3 998 | 135 | VRLQ|AGKP | nsp7 | ||
| 12 309 | 15 094 | 3 999 | 4 927 | 929 | TSMQ|SFTV | nsp9b | ||
| 15 095c | 16 891c | 4 928 | 5 526 | 599 | TVLQ|AAGM | nsp10 | ||
| 16 892c | 18 448c | 5 527 | 6 045 | 519 | IGLQ|AKPE | nsp11 | ||
| 18 449c | 19 465c | 6 046 | 6 384 | 339 | KALQ|SLEN | nsp12 | ||
| 19 466c | 20 365c | 6 385 | 6 684 | 300 | PQLQ|SAEW | nsp13 | ||
| 2 | PEDV | 297 | 626 | 1 | 110 | 110 | – | PCP CP1 |
| NC_003436 | 627 | 2 981 | 111 | 895 | 785 | FGRRGG|NIVPVD | PCP CP2 | |
| 2 982 | 7 847 | 896 | 2 517 | 1 622 | FKKKGG|GDVKFS | PCP CP3 | ||
| 7 848 | 9 287 | 2 518 | 2 997 | 480 | ANKKGA|GLPSFS | PCP CP4 | ||
| 9 288 | 10 193 | 2 998 | 3 299 | 302 | STLQ|AGLR | nsp2 | ||
| 10 194 | 11 033 | 3 300 | 3 579 | 280 | VNLQ|GGYV | nsp3 | ||
| 11 034 | 11 282 | 3 580 | 3 662 | 83 | SSVQ|SKLT | nsp4 | ||
| 11 283 | 11 867 | 3 663 | 3 857 | 195 | SMLQ|SVAS | nsp5 | ||
| 11 868 | 12 192 | 3 858 | 3 965 | 108 | VKLQ|NNEI | nsp6 | ||
| 12 191 | 12 596 | 3 966 | 4 100 | 135 | VRLQ|AGKQ | nsp7 | ||
| 12 597 | 15 376 | 4 101 | 5 027 | 927 | SIMQ|STDM | nsp9d | ||
| 15 377 | 17 167 | 5 028 | 5 624 | 597 | AVLQ|SAGL | nsp10 | ||
| 17 168 | 18 718 | 5 625 | 6 141 | 517 | SDLQ|ANEG | nsp11 | ||
| 18 719 | 19 735 | 6 142 | 6 480 | 339 | NNLQ|GLEN | nsp12 | ||
| 19 736 | 20 638 | 6 481 | 6 781 | 301 | PQLQ|ASEW | nsp13 | ||
Note that of the 24 coronavirus genomes, the predicted results by ZCURVE_CoV 2.0 are in complete agreement with those annotated by NCBI, except for the genomes of TGEV and PEDV, in which the predicted results are different from those annotated by NCBI. In this table the reasons for these conflicts are analyzed.
This conflict with the annotation is caused by the problematic annotation.
The locations are different from the annotation, which is caused by a questionable additional insertion of an amino acid residue in nsp9.
This conflict with the annotation is caused by the non-standard frameshift.