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. 2003 Oct 3;553(3):451–456. doi: 10.1016/S0014-5793(03)01091-3

Table 3.

Comparison of the predicted results for TGEV and PEDV with those annotated by NCBIa

Number Genome Location (bp)
Location (aa)
Length (aa) Cleavable peptide Feature
Start Stop Start Stop

1 TGEV 315 638 1 108 108 PCP CP1
NC_002306 639 2 951 109 879 771 KIARTG|RGAIYV PCP CP2
2 952 7 478 880 2 388 1 509 YNKMGG|GDKTVS PCP CP3
7 479 8 948 2 389 2 878 490 VSPKSG|SGFFDV PCP CP4
8 949 9 854 2 879 3 180 302 STLQ|SGLR nsp2
9 855 10 736 3 181 3 474 294 VNLQ|AGKV nsp3
10 737 10 985 3 475 3 557 83 STVQ|SKLT nsp4
10 986 11 570 3 558 3 752 195 TILQ|SVAS nsp5
11 571 11 903 3 753 3 863 111 TKLQ|NNEI nsp6
11 904 12 308 3 864 3 998 135 VRLQ|AGKP nsp7
12 309 15 094 3 999 4 927 929 TSMQ|SFTV nsp9b
15 095c 16 891c 4 928 5 526 599 TVLQ|AAGM nsp10
16 892c 18 448c 5 527 6 045 519 IGLQ|AKPE nsp11
18 449c 19 465c 6 046 6 384 339 KALQ|SLEN nsp12
19 466c 20 365c 6 385 6 684 300 PQLQ|SAEW nsp13
2 PEDV 297 626 1 110 110 PCP CP1
NC_003436 627 2 981 111 895 785 FGRRGG|NIVPVD PCP CP2
2 982 7 847 896 2 517 1 622 FKKKGG|GDVKFS PCP CP3
7 848 9 287 2 518 2 997 480 ANKKGA|GLPSFS PCP CP4
9 288 10 193 2 998 3 299 302 STLQ|AGLR nsp2
10 194 11 033 3 300 3 579 280 VNLQ|GGYV nsp3
11 034 11 282 3 580 3 662 83 SSVQ|SKLT nsp4
11 283 11 867 3 663 3 857 195 SMLQ|SVAS nsp5
11 868 12 192 3 858 3 965 108 VKLQ|NNEI nsp6
12 191 12 596 3 966 4 100 135 VRLQ|AGKQ nsp7
12 597 15 376 4 101 5 027 927 SIMQ|STDM nsp9d
15 377 17 167 5 028 5 624 597 AVLQ|SAGL nsp10
17 168 18 718 5 625 6 141 517 SDLQ|ANEG nsp11
18 719 19 735 6 142 6 480 339 NNLQ|GLEN nsp12
19 736 20 638 6 481 6 781 301 PQLQ|ASEW nsp13
a

Note that of the 24 coronavirus genomes, the predicted results by ZCURVE_CoV 2.0 are in complete agreement with those annotated by NCBI, except for the genomes of TGEV and PEDV, in which the predicted results are different from those annotated by NCBI. In this table the reasons for these conflicts are analyzed.

b

This conflict with the annotation is caused by the problematic annotation.

c

The locations are different from the annotation, which is caused by a questionable additional insertion of an amino acid residue in nsp9.

d

This conflict with the annotation is caused by the non-standard frameshift.