Table 2.

Brain regions of significant positive correlations of gray matter concentration decreases and combined olfactory function discrimination and identification score in patients with multiple sclerosis.

Cerebral region	Cluster size (mm3)	MNI coordinates			t-value	Cohen’s d	Height threshold
		x	y	z
Right middle temporal gyrus and temporal pole (BA 20, 21)	7780	−50	−8	−18	4.6	1.91	0.001
Right putamen		−34	−8	−5	4.45	1.85
Right amygdala		22	−2	−15	4.31	1.79
Right frontal superior and medial orbital gyrus		−15	35	−20	4.57	1.9
Straight gyrus (BA 11)		−9	33	−18	4.2	1.74
Right olfactory gyrus (BA 25)		−10	12	−15	3.77	1.57
Right anterior cingulate (BA 11)		−8	39	−4	4.2	1.76
Left amygdala (BA 34)	3490	29	2	−18	4.41	1.84
Left putamen		29	−2	−4	4.08	1.70
Left parahippocampus (BA 35)		19	−4	−27	3.75	1.56

BA: Brodmann area; MNI: Montreal Neurological Institute coordinates.

Cerebral regions are family-wise error corrected at the threshold of 0.001 of the cluster level.