Table 3.

ROC analysis for prediction of EDSS progression within 2 years.

	Cutoff value	Specificity (%)	Sensitivity (%)	AUC (SD)
Frontal ROI GMC	<0.69	74	34	0.68 (0.53–0.78)
Temporomesial/putamen ROI GMC	<0.79	82	58	0.81 (0.65–0.93)
DI-score	<24	94	63	0.86 (0.72–0.96)

AUC: area under the ROC curve; DI: discrimination and identification sum score; EDSS: expanded Disability Status Scale; GMC: gray matter concentration; ROC: receiver-operating characteristic; ROI: region of interest; SD: standard deviation.