Figure 3. Aging is associated with increases in K48 in the medial prefrontal cortex.
(A) Tissue was collected from the mPFC (adapted from Paxinos & Watson, 2007). (B) No significant differences in pRpt6 were noted. (C) 22-mo old animals displayed a tendency towards increased levels of K48 compared to 3-mo old animals, significant increases in K48 compared to 15-mo old animals. Data are presented as mean ± SEM. * denotes p < 0.05 in a Fisher’s LSD post hoc test.