Table 4.

Mean creatinine-adjusted concentrations of various HPHC biomarkers in current smokers by brand, tar group, and menthol status, NHANES 2007-2012.

	NNAL (ng/mg)			1HP (ng/mg)			2HP (ng/mg)			Sum HF (ng/mg)			Sum HPH (ng/mg)
	G. Mean	LCL	UCL	G. Mean	LCL	UCL	G. Mean	LCL	UCL	G. Mean	LCL	UCL	G. Mean	LCL	UCL
Brand	p<0.0001			p=0.0073			p=0.0609			p=0.0310			p=0.0227
Marlboro	0.34	0.32	0.36	0.31	0.26	0.37	14.13	12.88	15.85	3.02	2.69	3.47	0.58	0.50	0.66
Camel	0.23	0.20	0.28	0.32	0.22	0.48	13.18	9.12	19.05	2.69	1.91	3.80	0.51	0.36	0.72
Pall Mall	0.31	0.27	0.35	0.58	0.37	0.87	18.20	15.14	21.88	4.57	3.80	5.50	0.91	0.72	1.15
Newport	0.23	0.21	0.26	0.39	0.30	0.50	17.78	13.80	23.44	3.72	2.95	4.57	0.63	0.49	0.81
Other	0.30	0.26	0.33	0.28	0.25	0.31	17.38	15.85	19.50	3.39	3.02	3.80	0.58	0.52	0.63
Tar	p=0.4798			p=0.0071			p=0.0451			p=0.0996			p=0.0201
≤ 6mg	0.31	0.27	0.36	0.36	0.32	0.43	17.38	14.79	20.42	3.80	3.31	4.47	0.72	0.62	0.85
6.1-15mg	0.29	0.27	0.32	0.35	0.30	0.42	16.60	15.14	18.20	3.24	2.88	3.63	0.60	0.52	0.69
>15mg	0.30	0.28	0.34	0.26	0.23	0.31	13.80	11.75	16.22	3.09	2.57	3.63	0.54	0.46	0.62
Menthol	p=0.0412			p=0.0877			p=0.7297			p=0.9638			p=0.7910
No	0.31	0.28	0.33	0.30	0.27	0.34	15.85	14.45	17.38	3.31	2.95	3.63	0.59	0.54	0.66
Yes	0.28	0.25	0.31	0.39	0.30	0.52	15.49	12.30	19.05	3.24	2.57	4.07	0.62	0.49	0.76
	As (pg/mg)			Cd (pg/mg)			Co (pg/mg)			Pb (pg/mg)			Hg (pg/mg)
	G. Mean	LCL	UCL	G. Mean	LCL	UCL	G. Mean	LCL	UCL	G. Mean	LCL	UCL	G. Mean	LCL	UCL
Brand	p=0.5843			p=0.6117			p=0.8173			p=0.6146			p=0.4088
Marlboro	7.94	6.76	9.33	0.50	0.46	0.54	0.48	0.45	0.51	0.72	0.65	0.81	0.51	0.46	0.59
Camel	6.46	5.01	8.13	0.52	0.35	0.78	0.50	0.40	0.65	0.69	0.56	0.83	0.56	0.44	0.72
Pall Mall	7.41	5.13	10.47	0.51	0.43	0.62	0.49	0.40	0.60	0.83	0.69	1.02	0.41	0.32	0.52
Newport	8.71	7.08	10.96	0.50	0.44	0.58	0.50	0.44	0.56	0.72	0.56	0.93	0.54	0.45	0.63
Other	7.94	6.76	9.12	0.55	0.50	0.59	0.50	0.47	0.55	0.78	0.71	0.83	0.51	0.46	0.59
Tar	p<0.0205			p<0.3983			p<0.6538			p<0.4906			p<0.0636
≤ 6mg	9.33	7.94	10.96	0.56	0.48	0.65	0.51	0.46	0.56	0.71	0.63	0.78	0.60	0.51	0.69
6.1-15mg	7.41	6.76	8.13	0.51	0.49	0.55	0.49	0.47	0.52	0.74	0.69	0.79	0.49	0.45	0.54
>15mg	8.32	6.76	10.00	0.49	0.44	0.56	0.48	0.42	0.54	0.79	0.68	0.91	0.52	0.43	0.65
Menthol	p=0.2493			p=0.0045			p=0.2681			p=0.9191			p=0.3488
No	8.13	7.24	9.33	0.55	0.51	0.58	0.50	0.47	0.54	0.74	0.71	0.79	0.52	0.48	0.58
Yes	7.24	6.17	8.51	0.46	0.42	0.51	0.47	0.43	0.51	0.74	0.65	0.87	0.49	0.42	0.56

NOTE: All mean values adjusted for participant sex, age, race, education, cigarettes smoked per day, and serum cotinine