Table 2.

The association of depressive symptoms (CES-D Score) with allostatic load subsystem and meta-factor scores in the Jackson Heart Study

AL Z-Scores	Model	Overall (n = 2,670)		Women (n = 1,749)		Men (n = 921)
		Beta (95% CI)	p	Beta (95% CI)	p	Beta (95% CI)	p
Metabolic	1	0.002 (−0.001,0.005)	0.210	0.005 (0.001,0.008)	0.009	−0.001 (−0.007, 0.004)	0.702
	2	0.004 (0.001, 0.007)	0.005	0.006 (0.003, 0.009)	0.001	−0.0006 (−0.006, 0.005)	0.840
	3	0.004 (0.0006, 0.006)	0.018	0.005 (0.002, 0.009)	0.002	−0.001 (−0.007, 0.004)	0.681
	4	0.003 (0.0002, 0.006)	0.036	0.005 (0.001,0.008)	0.005	−0.002 (−0.007, 0.004)	0.590
Cardiovascular	1	0.004 (0.0007, 0.007)	0.018	0.006 (0.002, 0.010)	0.003	0.00008 (−0.006, 0.006)	0.980
	2	0.005 (0.002, 0.008)	0.003	0.007 (0.003, 0.010)	0.001	0.0004 (−0.006, 0.007)	0.897
	3	0.005 (0.001, 0.008)	0.007	0.006 (0.002, 0.010)	0.001	0.00003 (−0.006, 0.006)	0.992
	4	0.004 (0.0003, 0.007)	0.031	0.005 (0.002, 0.009)	0.005	−0.001 (−0.007, 0.005)	0.705
Immune	1	0.012 (0.007, 0.017)	<.001	0.010 (0.004, 0.015)	0.001	0.006 (−0.003, 0.016)	0.161
	2	0.009 (0.005, 0.014)	<.001	0.011 (0.005, 0.016)	<.001	0.007 (−0.002, 0.016)	0.138
	3	0.008 (0.003, 0.013)	0.002	0.009 (0.003, 0.015)	0.002	0.005 (−0.004, 0.014)	0.275
	4	0.007 (0.002, 0.011)	0.009	0.008 (0.002, 0.013)	0.008	0.003 (−0.006, 0.012)	0.474
Neuroendocrine	1	−0.003 (−0.006, 0.001)	0.190	−0.0002 (−0.005, 0.004)	0.933	−0.001 (−0.008, 0.006)	0.756
	2	0.0002 (−0.003, 0.004)	0.909	0.0006 (−0.004, 0.005)	0.783	−0.0008 (−0.007, 0.006)	0.820
	3	−0.0001 (−0.004, 0.004)	0.940	0.0003 (−0.004, 0.005)	0.905	−0.001 (−0.008, 0.006)	0.731
	4	−0.0007 (−0.004, 0.003)	0.737	−0.0001 (−0.005, 0.004)	0.951	−0.002 (−0.009, 0.005)	0.577
Meta-factor	1	0.004 (0.002, 0.006)	<.001	0.005 (0.002, 0.008)	<.001	0.001 (−0.003, 0.005)	0.618
	2	0.005 (0.002, 0.007)	<.001	0.006 (0.003, 0.009)	<.001	0.001 (−0.003, 0.006)	0.496
	3	0.004 (0.002, 0.006)	0.001	0.005 (0.003, 0.008)	<.001	0.0007 (−0.004, 0.005)	0.757
	4	0.003 (0.0008, 0.005)	0.007	0.004 (0.002, 0.007)	0.001	−0.0004 (−0.005, 0.004)	0.869

Note: p values of <0.05 considered statistically significant multivariable regression models examined associations among baseline depressive symptoms and AL at baseline; Model 1 unadjusted; Model 2 includes model 1 plus age, sex; Model 3 includes Model 2 plus education, occupation; Model 4 includes Mode 3 + smoking, physical activity; AL = allostatic load