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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Psychoneuroendocrinology. 2019 Jul 4;109:104369. doi: 10.1016/j.psyneuen.2019.06.020

Table 4:

Percent Mediation of Allostatic Load on the Association of Depressive Symptoms with Incident Coronary Heart Disease in the Jackson Heart Study


Overall (n = 2,670) Women (n = 1,749) Men (n = 921)

% Mediated p % Mediated p % Mediated p

Metabolic AL z-score 5.79 0.044 6.18 0.016 −2.16 0.840

Cardiovascular AL z-score 1.78 0.254 1.54 0.500 −0.19 0.920

Immune AL z-score 2.29 0.256 0.17 0.934 1.66 0.810

Neuroendocrine AL z-score −0.57 0.744 −0.03 0.952 −2.95 0.780

AL Meta-factor z-score 7.55 0.016 4.94 0.116 −0.20 0.990

Note: p values of <0.05 considered statistically significant; Models adjusted for age, sex, education, occupation, smoking and physical activity; AL = allostatic load