Table 2. Associated characteristics to positive tuberculin skin test prevalence in children (<15 years old) household contacts of adult patients with pulmonary tuberculosis (TB), in three Colombian cities, 2005-2009.
| Characteristic | N | Positive TST ( ≥5mm) | Positive TST ( ≥10 mm) | ||||
|---|---|---|---|---|---|---|---|
| n (%) | PR | (95%CI)* | n (%) | PR | (95%CI)* | ||
| Age in years n(%) | |||||||
| <1 | 19 | 7 (36.8) | 0.81 | (0.4 - 1.6) | 2 (10.5) | 0.37 | (0.1 - 1.4) |
| 1-4 | 137 | 66 (48.2) | 1 | (0.8 - 1.3) | 55 (40.1) | 1.03 | (0.8 - 1.3) |
| 5-9 | 153 | 74 (48.4) | 1 | 59 (38.6) | 1 | ||
| 10-14 | 149 | 96 (64.4) | 1.3 | (1.1 - 1.6)† | 84 (56.4) | 1.43 | (1.1 - 1.9)‡ |
| Sex n (%) | |||||||
| Male | 244 | 125 (51.2) | 1 | 105 (43.0) | 1 | ||
| Female | 214 | 118 (55.1) | 1.17 | (1.0 - 1.4) | 95 (44.4) | 1.17 | (1.0 - 1.4) |
| Low socioeconomic stratum | |||||||
| No | 54 | 24 (44.4) | 1 | 23 (42.6) | 1 | ||
| Yes | 401 | 217 (54.1) | 1.04 | (0.7 - 1.7) | 175 (43.6) | 0.84 | (0.5 - 1.4) |
| Nutritional condition | |||||||
| Normal | 255 | 139 (54.5) | 1 | 111 (43.5) | 1 | ||
| Underweight | 125 | 68 (54.4) | 1.07 | (0.9 - 1.3) | 61 (48.8) | 1.27 | (1.0 - 1.6)† |
| Overeight | 75 | 35 (46.7) | 0.96 | (0.7 - 1.3) | 28 (37.3) | 0.97 | (0.7 - 1.4) |
| BCG scar | |||||||
| No | 109 | 48 (44.0) | 1 | 35 (32.1) | 1 | ||
| Yes | 346 | 193 (55.8) | 1.34 | (1.0 - 1.7)† | 163 (47.1) | 1.52 | (1.1 - 2.1)† |
| History of another relative with TB** | |||||||
| No | 289 | 152 (52.6) | 1 | 122 (42.2) | 1 | ||
| Yes | 169 | 91 (53.8) | 1.05 | (0.8 - 1.3) | 78 (46.2) | 1.1 | (0.8 - 1.4) |
| Proximity to the index case | |||||||
| HHC slept in other household | 99 | 42 (42.4) | 1 | 27 (27.3) | 1 | ||
| HHC slept in same household | 224 | 119 (53.1) | 1.25 | (0.9 - 1.7) | 100 (44.6) | 1.61 | (1.1 - 2.4)† |
| HHC slept in same room | 135 | 82 (60.7) | 1.34 | (1.0 - 1.8) | 73 (54.1) | 1.79 | (1.1 - 2.8)† |
| Persons per room | |||||||
| <3 | 289 | 137 (47.4) | 1 | 108 (37.4) | 1 | ||
| ≥3 | 166 | 104 (62.6) | 1.27 | (0.9 - 1.8) | 90 (54.2) | 1.44 | (0.9 - 2.2) |
| Sputum smear load | |||||||
| + or ++ | 296 | 161 (54.4) | 1 | 129 (43.6) | 1 | ||
| +++ | 161 | 82 (50.9) | 1.07 | (0.8 - 1.4) | 71 (44.1) | 1.23 | (0.9 - 1.7) |
| Exposure time | |||||||
| ≤3 months | 303 | 146 (48.2) | 1 | 115 (38.0) | 1 | ||
| >3 months | 155 | 97 (62.6) | 1.24 | (1.0 - 1.6) | 85 (54.8) | 1.37 | (1.0 - 1.8)† |
TST: Tuberculin Skin Test. HHC: household contact.
* PR: Prevalence Ratio adjusted by all the other variables in the table and adjusted by family and city intraclass correlation.
** History of another relative with TB: had had any other relative with tuberculosis besides the identified index case in the cohort.
† p <0.05
‡ p <0.01