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. Author manuscript; available in PMC: 2020 May 18.
Published in final edited form as: Stem Cells Dev. 2008 Apr;17(2):325–332. doi: 10.1089/scd.2007.0079

FIG. 5.

FIG. 5.

A POTE gene cluster on the human chromosome 2. The human chromosome 2 (H) is a fusion of two ancestral chromosomes equivalent to the chimpanzee (C) chromosomes 2A and 2B. The centromere of chromosome 2A is retained (solid line) in the human chromosome 2 whereas that of chromosome 2B has been degenerated (dotted line). A POTE gene cluster is located in an ancestral pericentromeric region (2q21.1), which contains a total of five POTE genes. Genes in the POTE cluster are shown in blue (transcribed downward) and in red (transcribed upward). A dot-plot analysis reveals duplicons (arrows at the right) in this region. Homologous duplicons are depicted using the same color. The duplicons in green contain POTE genes. The palindromic region in yellow has been recently generated by a tandem duplication event.