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. 2020 May 15;8:e9187. doi: 10.7717/peerj.9187

Table 2. Cyclopia specific primers designed for testing HRM haplotype discrimination.

Primers used to screen haplotype variation in wild C. subternata populations are indicated in bold. Primer details provided include; non-coding cpDNA region the primers are located in, as well as each primers’ annealing temperature (Tm) in degrees Celcius, GC content, and sequence motif.

Region Primer Direction Tm (°C) GC (%) Sequence (5′→3′)
trnG intron MLT_C1 F 57.3 43.5 ACTCCTCTTCTATTCATGGGGA
MLT_C2 R 58.0 50.0
MLT_C3 F 61.8 40.9 TCAACGAACGATTCGAGGAATA
MLT_C4 R 61.1 45.5 TGCTTCAATCTCTCCTACCCAA
pctL-psbE intergenic spacer MLT_M1 F 58.0 43.5 TGTCGAGAACCCTTATACTCTCA
MLT_M2 R 58.7 47.6 TACCAAGGGTGTCTTTCGAGT
atpI-atpH intergenic spacer MLT_S1 F 64.3 50 ATTACAGATGAAACGGAAGGGC
MLT_S2 R 61.5 45.5 TGGGGGTTTCAAAGCAAAGG
MLT_S3 F 61.5 45.5 CCTTTGCTTTGAAACCCCCA
MLT_S4 R 66.4 36.5 TTCCCGTTTCATTCATTCACATTCA
ndhA intron MLT_U1 F 59.1 40.0 AGGTACTTCTGAATTGATCTCATCC
MLT_U2 R 62.2 52.4 GCAGTACTCCCCACAATTCCA
rpl32-trnL intergenic spacer MLT_V1 F 59.9 60.0 CTCCTTCCCTAAGAGCAGCG
MLT_V2 R 59.2 40.0 GTTGGAATAATCTGAATTAGCCGGA