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. 2020 May 8;11:372. doi: 10.3389/fphys.2020.00372

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Copyright © 2020 Li, Bai, Xu, Zhu, Liu and Duan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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KEGG pathway enrichment bubble plot of the differentially expressed miRNAs. X-axis label represents rich factor (rich factor = amount of differentially expressed genes enriched in the pathway/amount of all genes in the background gene set) and Y-axis label represents pathway. The size and color of the bubble represent the amount of differentially expressed genes enriched in the pathway and the enrichment significance (Q_ value is the P value corrected after multiple hypothesis testing), respectively.