Fig. 2. Loss of miR-146a in hTNFtg mice does not have an impact on the development of osteoporosis.
A-F, Quantitative histological analysis of tartrate-resistant acid phosphatase (TRAP) stained sections of the tibiae from wt (n = 11), miR-146a−/− (n = 14), hTNFtg (n = 14) and miR-146a−/−/hTNFtg (n = 16) mice. A, Bone volume per tissue volume B, Trabecular number C, Trabecular thickness D, Trabecular separation E, Number of Osteoclasts per bone perimeter and F, Number of Osteoblasts per bone perimeter (n = 11).