Table 1.
Demographic and clinical characteristics of two independent study cohorts from University of California, San Francisco (UCSF) and Davis (UCD). Mean (standard deviation) reported unless otherwise specified
| Demographic and Clinical Characteristics | UCSF (n = 344) | UCD (n = 485) |
|---|---|---|
| Age, y | 73.5 (7.3) | 76.9 (7.1) |
| % Female (n) | 55.8% (192) | 59.6% (289) |
| Education, y | 17.5 (2.0) | 14.3 (4.1) |
| Race (%, n) | ||
| White | 90.7% (303) | 50.2% (243) |
| Asian | 7.3% (25) | 0.01% (3) |
| Black | 0.9% (3) | 23.1% (112) |
| Hispanic/Latino | 0.0% (0) | 21.6% (105) |
| Other | 0.9% (3) | 0.01% (3) |
| Not reported | 2.9% (10) | 0% |
| Clinical Dementia Rating (CDR) | ||
| %CDR Total >0(n) | 2.3% (8) | 48.1% (233) |
| Sum of boxes (median, IQR) | 0 (0,0), range: 0, 1.5 | 0.5 (0,1.5), range: 0,13 |
| Mini Mental Status Exam (median. | 29(28,30) | 28 (26, 29) |
| IQR) | . | |
| Physical Activity | ||
| PASE | 130.7 (68.5), range: 5,390.4 | — |
| LEAF-Physical activities | — | 19.4 (4.4), range: 6, 30 |
| Cognitive Activity | ||
| CAS | 18.6 (3.1). range: 9,25 | — |
| LEAF-Cognitive activities | — | 29.22 (5.5), range: 13,50 |
| Total gray matter volume (L3) | 0.60 (0.06) | 0.57 (0.52) |
| White matter hyperintensity volume | 2.25 (0.88, 5.93) | 5.71 (2.23, 15.28) |
| (mm3) (median, IQR) | ||
| Global fractional anisotropy | 0.43 (0.012) | — |
MMSE range, 0-30; CDR sum of boxes range, 0-18; IQR, interquartile range; y, years; PASE, Physical Activity Scale for the Elderly; CAS, Cognitive Activity Scale.