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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Environ Toxicol Chem. 2020 Jan;39(1):118–130. doi: 10.1002/etc.4559

TABLE 1:

Summary of normalization approaches for metal ecotoxicity data sets from selected jurisdictions

Jurisdiction (year) Metal(s) Toxicity-modifying factor(s) Type of model Procedure summary Reference

United States (1983) Cd, Cu, Pb, Zn Hardness Linear • Model pooled for multiple species
• Species mean calculated
• Genus mean acute values used in SD
• ACR used for chronic criterion calculation
• One model for fish and invertebrates
• Species mean acute value calculated
• Genus mean acute values used in SD
• ACR used for chronic criterion calculation
• Chronic trophic level-specific models
• Species mean used in SSD
• DOC correction, driven by most sensitive species
• Chronic trophic level-specific models
• Species mean used in SSD
• DOC correction, driven by most sensitive species
• Chronic trophic level-specific models
• Species mean used in SSD
• Chronic trophic level-specific models
• Species mean used in SSD
• Chronic trophic level-specific models
• Species mean used in SSD
• Model developed from chronic single-species (fish) data set
• Species value used in SSD
• Separate acute and chronic models for fish and invertebrates
• Species mean chronic values calculated
• Genus mean chronic values used in SD
• Chronic models applied to acute SD
• Species-specific models proposed (chronic data)
•Species mean used in SSD
US Environmental Protection Agency (1987)
Hardness model in case study
United States (2007) Cu Several water chemistry parameters BLM US Environmental Protection Agency (2007)
United Kingdom (2009) Cu, Zn, Mn Cu Several water chemistry parameters BLM Marine MLR Environment Agency (2010, 2012a, 2012b, 2013)
European Union (2010) Ni Pb Several water chemistry parameters BLM MLR European Commission (2010a, 2010b)
France (2012) Cu, Zn Several water chemistry parameters BLM Tack (2012)
Italy (2016) Cu, Zn, Mn Several water chemistry parameters BLM Istituto Superiore per la Protezione e la Ricerca Ambientale (2016)
Sweden (2017) Cu, Zn Several water chemistry parameters BLM Swedish Marine and Water Authority (2016)
Canada (2018) Zn Hardness, pH, DOC MLR Canadian Council of Ministers of the Environment (2018)
MLR1-3 models in example
United States (2018) Al Hardness, pH, DOC MLR US Environmental Protection Agency (2018)
Australia/New Zealand (2018) Zn Hardness, pH, DOC MLR Australian and New Zealand Governments (2018b)

ACR = acute to chronic ratio; BLM = biotic ligand model; DOC = dissolved organic carbon; MLR = multiple linear regression; SD = sensitivity distribution; SSD = species sensitivity distribution.