Table 3.

Anthropometric data (Mean± SD) in the 2 groups of infants (<1 year) with Down Syndrome (DS) before and after treatment with L-thyroxine compared to DS of Group 1 (normal thyroid function)

Groups		Age (1) (yr)	Ht-SDS (1)	BMI-SDS (1)	Age (2) (yr)	HT-SDS (2)	BMI-SDS (2)	Delta Lenght-SDS	Delta BMI-SDS
TSH >5 and <12 mIU/L	Mean	0.48	-1.46	-1.04	4.4*	-1.99	0.43	-0.53	1.43
Treated	SDS	0.38	1.28	1.38	4.25	0.81	1.14	1.16	1.63
TSH >12 mIU/L	Mean	0.29	-2.43	-2.77*	4.4*	-2.24	0.69	0.20	3.46#
Treated	SDS	0.31	1.70	1.76	4.69	0.74	0.75	1.72	2.33
TSH <5 mIU/L	Mean	0.54	-1.75	-0.99	2.5*	-1.82	0.33	-0.07	1.32
Not Treated	SDS	0.39	2.51	1.33	1.00	1.53	1.62	1.43	2.14

Abbreviations: 1 = before treatment, 2 = after treatment with L-thyroxine .*p <0.05 Wilcoxon test before vs after; # p <0.05 ANOVA test between the 3 groups.