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Clinical scores of skin tolerability evaluation
| Skin alterations (erythema and oedema) | |||
| Erythema | Edema | ||
| No erythema | 0 | No edema | 0 |
| Slight erythema (hardly visible) | 1 | Very slight edema (hardly visible) | 1 |
| Clearly visible erythema | 2 | Slight edema | 2 |
| Moderate erythema | 3 | Moderate edema (about 1mm raised skin) | 3 |
| Serious erythema (dark red with possible formation of light eschars) | 4 | Strong edema (extended swelling even beyond the application area) | 4 |
