Table 5.
Comorbidities | Total (240 patients) | TDT (185 patients) | NTDT (55 patients) | P value: TDT vs. NTDT |
Splenectomy | 128 (53.3%) | 91 (49.1%) | 37 (67.2%) | 0.02 |
Osteopenia/Osteoporosis | 120 (50%) | 95 (51.3%) | 25 (45.4%) | 0.44 |
Cholelithiasis | 108 (45.0%) | 76 (41.0%) | 32 (58.1%) | 0.025 |
Cardiac complications | 42 (17.5%) | 33 (17.8%) | 9 (16.3%) | 0.8 |
Liver dysfunction | 24 (10%) | 21 (11.3%) | 3 (5.4%) | 0.2 |
Extramedullary hematopoiesis | 20 (8.3%) | 10 (5.4%) | 10 (18.1%) | 0.002 |
Kidney stones | 12 (5%) | 11 (5.9%) | 1 (1.8%) | 0.22 |
Pulmonary hypertension | 11 (4.6%) | 7 (3.7%) | 4 (7.2%) | 0.28 |
Renal complications | 10 (4.2%) | 10 (5.4%) | 0 (0%) | 0.08 |
Adrenal mass | 3 (1.3%) | 3 (1.6%) | 0 (0%) | 0.34 |