Table 6.
Endocrine complications | Total TDT and NTDT (240 patients) | TDT (185 patients) | NTDT (55 patients) | P value: TDT vs. NTDT |
HH | 51 (21.3%) | 47 (25.4%) | 4 (7.2%) | 0.004 |
With children / Without children | 31/20 | |||
Non- insulin dependent diabetes | 28 (11.7%) | 26 (14.0%) | 2 (3,6%) | 0.03 |
With children/Without children | 24/4 | |||
Primary hypothyroidism | 24 (10.0%) | 22 (11.8%) | 2 (3.6%) | 0.07 |
With children/Without children | 18/6 | |||
Central hypothyroidism | 20 (8.3%) | 19 (10.2%) | 1 (1.8%) | 0.04 |
With children/Without children | 13/7 | |||
Hypoparathyroidism | 18 (7.5%) | 15 (8.1%) | 3 (5.4%) | 0.51 |
With children/Without children | 14/4 | |||
Insulin dependent diabetes | 14 (5.8%) | 13 (7.0%) | 1 (1.8%) | 0.15 |
With children/Without children | 8/6 | |||
Growth hormone deficiency | 8 (3.3%) | 6 (3.2%) | 2 (3.6%) | 0.88 |
With children/Without children | 4/4 | |||
Latent hypocortisolism | 4 (1.7%) | 3 (1.6%) | 1 (1.8%) | 0.92 |
With children/Without children | 4/0 | |||
Thyroid cancer | 3 (1.3%) | 3 (1.8%) | 0 (0%) | 0.34 |
With children/Without children | 2/1 |
Legend: HH = Hypogonadotropic hypogonadism