Table 7.
Iron chelation therapy and serum ferritin levels before, during and after paternity
| TDT patients | Serum ferritin at least 2 years before paternity (A) | Serum ferritin in the year of the first paternity (B) | Last serum ferritin level (C) | P value: A vs B | P value: B vs C |
| Mean | 2581.0 ± 191.5 | 2211.8 ± 181.8 | 1825.7 ± 179.9 | 0.115 | <0.001 |
| Lower Bound | 2202.7 | 1852.0 | 1470.7 | ||
| Upper Bound | 2959.2 | 2571.6 | 2180.7 | ||
| Median | 2000.0 | 1500.0 | 949.5 | ||
| Standard Deviation (SD) | 2475.6 | 2089.5 | 2413.7 | ||
| Minimum | 105 | 105 | 91 | ||
| Maximum | 13085 | 9495 | 15484 | ||
| Interquartile Range | 2700 | 2508 | 1626 | ||
| NTDT patients | (A) | (B) | (C) | ||
| Mean | 1059.9 ± 162.73 | 1387.1 ± 328.31 | 1165.5 ± 222.9 | 0.48 | 0.083 |
| Lower Bound | 731.0 | 719.1 | 717.7 | ||
| Upper Bound | 1388.8 | 2055.0 | 1613.4 | ||
| Median | 620.0 | 600.0 | 559.0 | ||
| Standard Deviation (SD) | 1041.9 | 1914.3 | 1592.3 | ||
| Minimum | 100 | 100 | 105 | ||
| Maximum | 5000 | 9500 | 9500 | ||
| Interquartile Range | 1210 | 1430 | 943 |