Table 1.

Reviews (year)	Strengths	Limits of the study	Practical utility
Mariotti P. et al. Movement Disorders 2007	First critical review Accurate description of two personal cases with one year of follow-up	No clear information about dosage of drugs No information about trigger factors and warning sign	Not available
Grosso S. et al. European Journal of Paediatric Neurology 2012	Detailed description of personal cases with dosage of drugs and clinical course Flow chart management	Limited number of subjects No clear information about dystonia-targeted therapy No description about how to prevent SD	Therapy in PICU
Fasano A. et al. Movement Disorders 2012	Comprehensive systematic analysis of SD Large case series Information about successful treatment strategies Outcome description	No information about dosage of drugs and timing of pharmacological intervention No specific for pediatric population	Diagnosis
Allen ML. et al Developmental Medicine & Child Neurology 2014	First description about how to prevent SD in hospitalized child Screening for dystonia severity (grade) and action plan with overview of the management of SD and how to treat complications	No distinction in management depending on underlying etiology	Diagnosis and Therapy
Lopez MR and Fasano A. Movement Disorders 2017	Update on. phenomenology, progression and outcome Underlying etiology and pathophysiology Differential diagnosis	No description about how to prevent SD No information about dosage of drugs and timing of pharmacological intervention	Diagnosis
Lumsden DE et al. Curr Opinion Neurology 2017	Whole update on SD Screening for dystonia severity and action plan	No information about treatment outside PICU and dosage of dystonia-targeted therapy or calibrating sedation	Multilevel intervention and pharmacological management in PICU