Figure 3. 3K7 binds directly to LMO2.

STD-NMR spectra for compound alone (green) or in complex with LMO2 (red) were compared to reference ¹H spectra (blue) for (A) 3K7 and (B) 5C7. Box highlights peaks indicative of binding observed in the aromatic region of the 3K7 spectrum. (C) Curve showing normalised fluorescence data from MST experiments with LMO2 and (D) SCL/E47 in presence of increasing 3K7 concentration. The bottom panel in C shows residuals between the data and the fit line. Error bars represent standard deviation, n = 4.