Table 2. Clinical characteristics of neonatal cases of coronavirus disease 2019 described thus far in English literature.
Author (Reference) | Zeng et al. (3) | Zeng et al. (3) | Zeng et al. (3) | Kamali et al. (7) | Patek et al. (10) | Coronado et al. (11) | Alzamora et al. (4) | Hu et al. (5) | Current case |
Gestational age (Weeks) | 40 | 40 4/7 | 31 2/7 | Full-term | 39 | 36 | 33 | 40 | 39 |
Day of life when illness started | 2 | 0 | 0 | 15 | 14 | 21 | 0 | Asymptomatic | 22 |
Mode of delivery | CS | CS | CS | CS | CS | Not available | CS | CS | Vaginal |
Presentation | Fever, lethargy | Fever, lethargy, vomiting | Respiratory distress | Fever, tachypnea, and mottling | Fever, erythema of digits, poor feeding | Congestion, tachypnea, reduced feeding | Respiratory insufficiency (?secondary to maternal general anesthesia) | N/A | Fever, decreased oral intake |
Abnormal labs | Abnormal Procalcitonin | Leukocytosis, lymphopenia, elevated creatine kinase | Abnormal coagulation profile | None | Neutropenia, elevated liver enzymes, MRSA from wound cultures | Rhinovirus positive, elevated CRP, Procalcitonin | N/A | None | None |
Chest radiography | Pneumonia | Pneumonia | Pneumonia | Normal | Bilateral perihilar streaking | Bilateral infiltrates | Normal | Normal | Normal |
SARS-CoV-2 testing | NP, rectal swabs + PCR | NP, rectal swabs + PCR | NP, rectal swabs + PCR | NP + PCR | NP + PCR | NP + PCR | NP + PCR | Throat swab + PCR | NP + PCR |
Probable mode of transmission | ? Vertical | ? Vertical | ? Vertical | Horizontal | Horizontal | Horizontal | ?Vertical | ? Vertical | Horizontal |
Outcome | Recovered | Recovered | Recovered | Recovered | Recovered | Recovered | Recovered | Recovered | Recovered |