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. 2020 May 18;15(5):e0232877. doi: 10.1371/journal.pone.0232877

Table 4. Association between temperature and early and late preeclampsia, stratified by ethnicity and “warm”/”cold” pregnancies; multivariable regression models.

Bedouin-Arab ethnicity Jewish ethnicity
a. Early PE "Cold" Pregnancies "Warm" Pregnancies "Cold" Pregnancies "Warm" Pregnancies
Variable PV RR CI PV RR CI PV RR CI PV RR CI
Temperature trimester 1 <0.001 0.06 0.02–0.18 <0.001 436.7 89–2139 <0.001 0.08 0.03–0.27 <0.001 111.45 27.6–450
Temperature trimester 2 0.27 0.67 0.32–1.4 0.01 0.2 0.06–0.69 0.59 1.2 0.57–2.7 0.003 0.18 0.06–0.55
Temperature trimester 3 <0.001 0.06 0.02–0.17 <0.001 155.2 42–569 0.001 0.12 0.03–0.39 <0.001 24.2 7.7–76
b. Late PE
Variable PV RR CI PV RR CI PV RR CI PV RR CI
Temperature trimester 1 0.58 0.91 0.64–1.29 0.02 1.62 1.08–2.45 0.19 1.03 0.88–1.98 0.27 1.33 0.8–2.2
Temperature trimester 2 0.59 0.94 0.74–1.18 0.95 0.99 0.7–1.4 0.15 1.02 0.93–1.57 0.23 1.3 0.85–1.98
Temperature trimester 3 0.31 0.82 0.57–1.2 0.02 1.48 1.07–2.04 0.65 1.01 0.72–1.7 0.12 1.38 0.92–2.03

Results of the GEE Poisson multivariable regression models, with early and late preeclampsia as an outcome. The models included averaged temperatures for each trimester in IQR units as the primary exposure at study and were adjusted to maternal age, gravidity, multiple delivery and a history of preeclampsia in the past deliveries. Results are presented by the relative risks (RR), their 95% confidence intervals (CI) and p-values.