Table 7.
Radiological findings and treatments used in newborns and infants ≤ 3 months of age with documented SARS-CoV-2 infection
| Author | N | Radiology findings | Treatment | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Abnormal | Chest X-ray | CT-scan | GGO | Local patchy | Bilateral patchy | Normal | PICU | MV | Symptomatic alone | Antibiotic | IVIg | IFN | ||
| Wang [63] | 1 (1 m) | 1 (100%) | 0 | 1 (100%) | 0 | 1 (100%) | 0 | 0 | ||||||
| Zhu [65] | 10 (8 m) | 7 (70%) | 10 (100%) | 0 | 1 (10%) | 1 (10%) | 3 (30%) | 3 (30%) | 0 | 0 | 9 (90%) | 0 | 1 (10%) | 0 |
| Lu [66] | 3 | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
| Zeng** [68] | 1 (1 m) | 1 (100%) | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
| Wang [70] | 1 | NR | NR | NR | NR | NR | NR | NR | 0 | 0 | 0 | 0 | 0 | 1 (100%) |
| Zeng [23] | 3 (3 m) | 3 (100%) | 3 (100%) | 0 | 0 | 3 (100%) | 0 | 0 | 1 (33%) | 1 (33%) | 2 (67%) | 1 (33%) | 0 | 0 |
| Kamli-Aghdam [73] | 1 (1 m) | 0 | 1 (100%) | 0 | 0 | 0 | 0 | 1 (100%) | 1 (100%) | 0 | 0 | 1 (100%) | 0 | 0 |
| Canarutto [74] | 1 (1 m) | 0 | 1 (100%) | 0 | 0 | 0 | 0 | 1 (100%) | 0 | 0 | 1 (100%) | 0 | 0 | 0 |
| Dong [22] | 1 | 0 | 0 | 1 (100%) | 0 | 0 | 0 | 1 (100%) | 0 | 0 | 0 | 0 | 0 | 0 |
| Buonsenso [82] | 2 (2 m) | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
| Han [83] | 1 | 0 | 1 (100%) | 0 | 0 | 0 | 0 | 1 (100%) | 0 | 0 | 1 (100%) | 0 | NR | NR |
| Total | 25 (15 m) | 12 | 16 | 2 | 1 | 5 | 3 | 7 | 2 | 1 | 2 | 12 | 1 | 2 |
| % | 48 | 64 | 8 | 4 | 20 | 12 | 28 | 8 | 4 | 8 | 48 | 4 | 8 | |
SARS-CoV-2 severe acute respiratory syndrome–Coronavirus-2, NR not reported, GGO ground-glass opacities, PICU pediatric intensive care unit, MV mechanical ventilation, IVIg intravenous immunoglobulin, CCS corticosteroids, IFN interferon
**Studies included in the review by Henry et al. [67]