Table 4. Seizure frequency changing during pregnancy (n = 48).
| Variables | Worse (n = 9, 18.8%) | Same (n = 23, 47.9%) | Improve (n = 16, 33.3%) | P value | |
|---|---|---|---|---|---|
| Age, yr | 32.00 ± 3.08 | 33.91 ± 3.70 | 32.63 ± 5.74 | 0.276 | |
| BMI | |||||
| First visit | 22.41 ± 6.06 | 21.76 ± 2.91 | 21.43 ± 4.56 | 0.787 | |
| Delivery | 27.35 ± 3.82 | 26.95 ± 3.83 | 26.61 ± 5.36 | 0.990 | |
| No. of AEDs | 1.78 ± 0.83 | 1.4 ± 0.89 | 1.5 ± 0.73 | 0.374 | |
| Delivery type | 0.544 | ||||
| Vaginal delivery | 2 (22.22) | 8 (34.78) | 7 (43.75) | ||
| C-sec | 7 (77.78) | 15 (65.21) | 9 (56.25) | ||
| Gestational period, wk | 37.44 ± 1.74 | 37.87 ± 2.07 | 37.94 ± 2.46 | 0.452 | |
| EEG, abnormal (W = 9, S = 23, I = 16, n = 48) | 7 (77.8) | 15 (65.2) | 13 (81.3) | 0.631 | |
| MRI, abnormal (W = 5, S = 16, I = 12, n = 33) | 3 (60.0) | 10 (62.5) | 3 (25.0) | 0.454 | |
| Seizure severity (n = 48) | 0.011a | ||||
| A | 1 (12.5) | 18 (81.8) | 8 (50.0) | ||
| B | 1 (12.5) | 2 (9.1) | 4 (25.0) | ||
| C | 0 (0.0) | 0 (0.0) | 1 (6.3) | ||
| D | 5 (62.5) | 2 (9.1) | 3 (18.8) | ||
| Baby | |||||
| Sex, male | 2 (10.0) | 11 (55.0) | 7 (35.0) | 0.409 | |
| Height | 49.56 ± 4.67 | 48.43 ± 4.08 | 49.79 ± 2.68 | 0.516 | |
| Weight | 2,757.78 ± 744.91 | 2,883.75 ± 776.12 | 3,050.63 ± 697.10 | 0.466 | |
| Head circumference | 34.06 ± 1.52 | 33.19 ± 2.99 | 33.32 ± 2.02 | 0.759 | |
| Apgar score | |||||
| 1 min (n = 46) | 7.57 ± 0.53 | 7.50 ± 0.83 | 7.47 ± 0.62 | 0.688 | |
| 5 min (n = 46) | 8.86 ± 0.38 | 8.83 ± 0.48 | 8.80 ± 0.54 | 0.883 | |
Values are presented as mean ± standard deviation or number (%).
BMI = body mass index, AED = antiepileptic drug, EEG = electroencephalography, MRI = magnetic resonance imaging.
aStatistical significance (P < 0.05).