Table 3. Prediction model of Δheight SDS during 1st year of GH treatment in prepubertal Korean children with idiopathic GHD (n = 345).
| IGHD | Parameter estimate | Rank of predictor | Partial variability (R2 × 100) | P value | Variance inflation |
|---|---|---|---|---|---|
| Intercept | 1.06 | < 0.001 | 0 | ||
| Age at start of GH, yr | −0.05 | 1 | 12.77 | < 0.001 | 1.10448 |
| MPH SDS – height SDS | 0.09 | 2 | 5.09 | < 0.001 | 1.01768 |
| BMI SDS | 0.05 | 3 | 1.71 | 0.015 | 1.09293 |
| Total explained variability (R2 × 100) | 19.57 | ||||
| Error SD | 0.31 |
The estimated regression equation is as follows Δheight SDS during 1st year of GH treatment = 1.06 − 0.05 × age + 0.09 × (MPH SDS – height SDS) + 0.05 × BMI SDS.
SDS = standard deviation score for chronological age, GH = growth hormone, GHD = growth hormone deficiency, IGHD = idiopathic GHD, MPH = mid parental height, BMI = body mass index, Δheight SDS = change in height SDS between before and after 1 year GH treatment, Error SD = standard deviation of error.