Table 6.
Characteristics of Patients with G3-HCV Cirrhosis Who Showed no Response to Past and Current Antiviral Treatments
| Patient | Age, yr/sex | Past treatment | HCV RNA >800,000 IU/mL | CPT class | Treatment | NS5A/NS5B resistance test, posttreatment |
|---|---|---|---|---|---|---|
| 1 | 50/M | Relapsed after PegIFN/RBV | No | A | DCV/SOF/RBV 1,000 mg | Not performed |
| 2 | 56/F | None | Yes | A | DCV/SOF | Y93H |
| 3 | 52/M | Relapsed after PegIFN/RBV | No | A | DCV/SOF | Y93H |
| 4 | 50/M | None | No | B | DCV/SOF | Y93H |
| 5 | 60/M | No response to PegIFN/RBV | Yes | A | DCV/SOF | Y93H |
| 6 | 52/M | No response to PegIFN/RBV | No | A | DCV/SOF/RBV 1,000 mg | Y93H-L159F- L31M |
| 7 | 52/M | Relapsed after SOF/RBV | No | A | DCV/SOF | Y93H |
| 8 | 48/F | None | No | B | DCV/SOF | Y93H |
| 9 | 46/M | None | Yes | B | DCV/SOF/RBV 800 mg | Y93H |
| 10 | 41/M | None | No | B | DCV/SOF | Y93H |
| 11 | 57/M | No response to PegIFN/RBV | Yes | A | DCV/SOF | Y93H |
| 12 | 61/M | Relapsed after PegIFN/RBV | Yes | A | DCV/SOF | None |
G3-HCV, genotype 3 hepatitis C virus; CPT, Child-Pugh-Turcotte; M, male; F, female; PegIFN, pegylated interferon; RBV, ribavirin; DCV, daclatasvir; SOF, sofosbuvir.