Table 1.

Criteria of the International Society for Cellular Therapy for Defining MSCs

Adherence to plastic	Surface antigen expression		Multipotent differentiation
	Positive (≥ 95%)	Negative (≤ 2%)
Adherence to plastic in standard culture conditions	CD73	CD14/CD11b	Differentiation potential into osteoblasts, adipocytes, chondroblasts, which is demonstrated by staining of in vitro cultured cells
	CD90	CD79a/CD19
	CD105	CD34
		CD45
		HLA-DR

MSCs, mesenchymal stem cells; HLA-DR, human leukocyte antigen–DR isotype.