TABLE 1.
Characteristics of Cirrhotic Patients Receiving TEG
| All Cirrhotics (n=106) | CTP A (n=25) | CTP B (n=25) | CTP C (n=56) | |
|---|---|---|---|---|
| Age [mean (SD)] | 58.0 (10.8) | 63.1 (10.9) | 61.2 (8.2) | 54.3 (10.6) |
| Gender, male (%) | 62.3 | 80 | 51.5 | 51.8 |
| Reason for getting TEG | ||||
| Bleeding | 30 | 9 | 8 | 13 |
| Before liver transplant | 42 | 9 | 11 | 22 |
| Before other procedure | 19 | 3 | 4 | 13 |
| Evaluation of coagulopathy, bleeding risk stratification | 15 | 5 | 2 | 8 |
| Cause of liver diagnosis | ||||
| Alcoholic | 32 | 11 | 6 | 25 |
| HCV | 43 | 16 | 15 | 12 |
| NASH | 16 | 2 | 3 | 11 |
| Autoimmune | 3 | 0 | 0 | 3 |
| HBV | 3 | 1 | 1 | 1 |
| PSC | 5 | 1 | 1 | 3 |
| PBC | 4 | 0 | 0 | 4 |
| Cryptogenic | 4 | 0 | 3 | 1 |
| Other | 2 | 1 | 0 | 2 |
| Na-MELD [mean (SD)] | 20.08 (10.7) | 9.56 (3.9) | 14.76 (4.8) | 27.16 (9.4) |
| Platelets [mean (SD)] | 108.33 (84.2) | 155.72 (92.3) | 113.68 (105.7) | 84.79 (58.0) |
| INR [mean (SD)] | 2.10 (2.1) | 1.13 (0.2) | 1.57 (0.4) | 2.46 (1.3) |
| Patients receiving any blood product 24 hours after TEG | ||||
| Packed red blood cells | 51 | 4 | 19 | 36 |
| Platelets | 39 | 5 | 15 | 27 |
| FFP or cryoprecipitate | 46 | 2 | 16 | 36 |
| Prothrombin complex concentrate | 3 | 0 | 1 | 2 |
| Needing to get another TEG over 24 h after for continued bleeding | 18 | 1 | 4 | 13 |
| Cancer diagnosis | 41 | 11 | 17 | 13 |
| Bleeding diathesis | 2 | 1 | 0 | 1 |
| DVT prophylaxis during TEG study | 8 | 2 | 0 | 6 |
| Therapeutic anticoagulation during TEG study | 5 | 0 | 2 | 3 |
CTP indicates Child-Turcotte-Pugh; DVT, deep vein thrombosis; FFP, fresh frozen plasma; HBV, hepatitis B virus; HCV, hepatitis C virus; INR, international normalized ratio; Na-MELD, sodium Model for End-Stage Liver Disease; NASH, nonalcoholic steatohepatitis; PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis; TEG, thromboelastography