Table 3.
Spasticity Referral Tool Performance
| Primary Care Provider | Subjects Evaluated by Rater and Reference Standard | Spasticity Prevalence (Positive Pre-Test Probability)a | Sensitivity (95% CI) | Positive Likelihood Ratio (95% CI)b | Spasticity Prevalence in Subjects Referred (Positive Post-Test Probability)c | Specificity (95% CI) | Negative Likelihood Ratio (95% CI)d | Spasticity Prevalence in Subjects Not Referred (Negative Post-Test Probability)e |
|---|---|---|---|---|---|---|---|---|
| Primary care physician (PCP) | n=43 | 30% | 92% (64–100%) |
4.0 (2.0–7.7) |
63% | 78% (58-90%) |
0.10 (0.02–0.67) |
4% |
| Nurse practitioner (NP) | n=45 | 33% | 80% (52–96%) |
1.7 (1.1–2.7) |
46% | 53% (34–72%) |
0.38 (0.13–1.1) |
16% |
Notes: aSpasticity prevalence in the study population was 35% (17/49 subjects evaluated by the reference standard). Overlap between the reference standard and subjects evaluated by the PCP and NP was 43 and 45, respectively; therefore, prevalence within those subsets are presented for probability estimates. bCalculated as sensitivity/(1-specificity). cProbability of spasticity being present after rater referral to a spasticity specialist. dCalculated as (1-sensitivity)/specificity. eProbability of spasticity being present after rater deciding not to refer to a spasticity specialist.