Table 1.

Gene-set association results of dopaminergic (DOPA) and circadian rhythm (CIRCA) systems with ADHD, BMI, and obesity.

	DOPAa	CIRCAb
ADHDc	5.81 × 10−3	0.521
BMId	1.63 × 10−5	1.28 × 10−3
Obesitye	0.050	0.205

Values shown are association P values. Significant associations are highlighted in bold

^aDOPA gene-set analyses are based on 261, 245, and 248 genes from the ADHD, BMI, and obesity GWAS summary statistics, respectively

^bCIRCA gene-set analyses are based on 281, 272, and 273 genes from the ADHD, BMI, and obesity GWAS summary statistics, respectively

^cEuropean ancestry iPSYCH-PGC ADHD GWAS [4]

^dGIANT-UK Biobank BMI GWAS [11]

^eGIANT obesity (class I) GWAS [12]