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. 2020 May 18;10:8136. doi: 10.1038/s41598-020-65115-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Functional enrichment analyses of aging models. (a) GO-terms enrichment analysis using the differentially expressed mRNAs in each aging model after the comparison with wild-type 12 week-old mice. Gene-Concept networks visualizing the individual protein-coding genes associated to the GO-terms found enriched for (b) naturally-aged and (c) Harlequin mice.