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. 2020 May 18;11:2461. doi: 10.1038/s41467-020-16300-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Immunohistochemistry analysis of TFEB in wild-type (WT) liver at the indicated stages showing prominent signaling in bile ductules. Arrows indicate ductal cells. b, c Representative immunofluorescence stains for TFEB/HNF4α (b) and TFEB/SOX9 (c) showing TFEB levels in the central (CV) and in the portal (PV) vein area. Scale bar 20 μm. Micrographs are representative of five mice of each stage.