Table 2.
Characteristics of all chronic subdural hematoma patients and treatment subgroups
Total sample n = 1133 | Non-operative treatment n = 168 | Operative treatment n = 965 | p value | ||||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Median age, years, IQR | 76 | 67–83 | 79 | 68–86 | 76 | 66–82 | 0.001 |
Sex | |||||||
Men | 736 | 65.0 | 102 | 60.7 | 634 | 65.7 | 0.21 |
Traumatic etiology | 672 | 59.3 | 107 | 63.7 | 565 | 58.5 | 0.21 |
Comorbidity | |||||||
Cardiovascular disease | 644 | 56.8 | 96 | 57.1 | 548 | 56.8 | 0.93 |
Diabetes | 178 | 15.7 | 27 | 16.1 | 151 | 15.6 | 0.89 |
Chronic alcohol abuse | 126 | 11.1 | 20 | 11.9 | 106 | 11.0 | 0.73 |
Cerebrovascular disease | 124 | 10.9 | 24 | 14.3 | 100 | 10.4 | 0.13 |
Dementia | 99 | 8.8 | 26 | 15.7 | 73 | 7.6 | 0.001 |
Pulmonary disease | 68 | 6.0 | 16 | 9.5 | 52 | 5.4 | 0.05 |
Epilepsy | 32 | 2.8 | 3 | 1.8 | 29 | 3.0 | 0.38 |
Neurodegenerative disease | 20 | 1.8 | 7 | 4.2 | 13 | 1.3 | 0.01 |
Hydrocephalus | 9 | 0.8 | 0 | 0 | 9 | 0.9 | 0.21 |
Medication | |||||||
Antiplatelet | 268 | 23.7 | 36 | 21.4 | 232 | 24.0 | 0.46 |
Warfarin | 187 | 16.5 | 26 | 15.5 | 161 | 16.7 | 0.69 |
Warfarin AND antiplatelet | 23 | 2.0 | 2 | 1.2 | 21 | 2.2 | 0.40 |
Admission GCS | |||||||
13–15 | 1007 | 88.9 | 157 | 93.5 | 850 | 88.1 | 0.04 |
9–12 | 91 | 8.0 | 8 | 4.8 | 83 | 8.6 | 0.91 |
3–8 | 35 | 3.1 | 3 | 1.8 | 32 | 3.3 | 0.29 |
Admission mRS 0–3 | 580 | 51.2 | 121 | 72.0 | 459 | 47.6 | < 0.001 |
Symptoms | |||||||
Hemiparesis | 444 | 39.2 | 9 | 5.4 | 435 | 45.1 | < 0.001 |
Vertigo or postural instability | 408 | 36.0 | 35 | 20.8 | 373 | 38.7 | < 0.001 |
Disorientation/memory impairment | 390 | 34.4 | 54 | 32.1 | 336 | 34.8 | 0.50 |
General malaise | 367 | 32.4 | 50 | 29.8 | 317 | 32.8 | 0.43 |
Headache | 340 | 30.0 | 28 | 16.7 | 312 | 32.3 | < 0.001 |
Aphasia | 245 | 21.6 | 9 | 5.4 | 236 | 24.5 | < 0.001 |
Seizure | 117 | 10.3 | 28 | 16.7 | 89 | 9.2 | 0.003 |
Nausea and/or vomiting | 60 | 5.3 | 7 | 4.2 | 53 | 5.5 | 0.48 |
IQR Interquartile range; GCS Glasgow Coma Scale; mRS Modified Rankin Scale