Table 2.

Top Networks identified in circulating lymphocytes and monocytes by Ingenuity Pathway Analysis (IPA) in each pairwise comparison of the patients groups.

Pairwise comparison	Associated Network Functions	Score
T2DMpoorly-DL-P versus H	Cell Cycle, Cell-To-Cell Signaling and Interaction, Hematological System Development and Function	33
	Cellular Movement, Immune Cell Trafficking, Connective Tissue Disorders	31
	Antimicrobial Response, Inflammatory Response, Dermatological Diseases and Conditions	31
	Cellular Movement, Cellular Development, Cellular Growth and Proliferation	31
	Cellular Movement, Cancer, Organismal Injury and Abnormalities	29
T2DMwell-DL-P versus H	Cellular Movement, Immune Cell Trafficking, Cell-mediated Immune Response	37
	Infectious Diseases, Immunological Disease, Connective Tissue Disorders	33
	Hematological System Development and Function, Tissue Morphology, Cell-To-Cell Signaling and Interaction	33
	Cardiovascular System Development and Function, Tissue Morphology, Digestive System Development and Function	29
	Cell Death and Survival, Inflammatory Response, Organismal Injury and Abnormalities	27
DL-P versus H	Cellular Movement, Immune Cell Trafficking, Cell-To-Cell Signaling and Interaction	37
	Cellular Assembly and Organization, Cancer, Organismal Injury and Abnormalities	33
	Dermatological Diseases and Conditions, Developmental Disorder, Hereditary Disorder	33
	Cell-To-Cell Signaling and Interaction, Cell Morphology, Cellular Movement	31
	Organismal Development, Cardiovascular System Development and Function, Hematological System Development and Function	20
P versus H	Cell Death and Survival, Cell Signaling, Post-Translational Modification	34
	Dermatological Diseases and Conditions, Organismal Injury and Abnormalities, Cancer	34
	Inflammatory Disease, Inflammatory Response, Organismal Injury and Abnormalities	28
	Cardiac Arrhythmia, Cardiovascular Disease, Organismal Injury and Abnormalities	28
	Cellular Compromise, Inflammatory Response, Infectious Diseases	23