Figure 6.

Systemic inflammation-induced neuroinflammation is blocked in the two-week old offspring of maternal LB supplemented mice. Neuroinflammation markers Il6 (a), Il1β (b), Nos2 (d), Ccl3 (e) and Tnf (f), but not Nos1 (c), evaluated by RT-PCR, were upregulated by i.p. injection of IL-1β after four hours in two weeks old mice (n = 5–6). Maternal exposure of LB blocked the Il-1β induced increased expression of these markers (n = 6–7). Data were normalized to Gapdh gene expression and are presented as mean ± SEM. Bars with ⎴ denote significant difference between experimental groups (at least p < 0.05).