Table 3.
Key differential diagnosis for glomangiopericytoma and suggested immunohistochemical panel
| Benign/borderline tumors | Suggested immunoprofile |
|---|---|
| Glomangiopericytoma | SMA+, STAT6-, TLE1-, CD31-, CD117-, SOX10-, S100-, EMA- |
| Solitary fibrous tumor | STAT6+, TLE1- |
| Myopericytoma | Nuclear beta catenin-, STAT6-, TLE1- |
| Lobular capillary hemangioma | CD31+, SMA-, STAT6-, TLE1- |
| Nasopharyngeal angiofibroma | CD117+, AR+, SMA-, STAT6-, TLE1- |
| Benign peripheral nerve sheath tumor | SOX10+, S100+, STAT6-, TLE1- |
| Meningioma | EMA+, PR+, STAT6-, TLE1- |
| Malignant tumors | Suggested immunoprofile |
|---|---|
| Monophasic synovial sarcoma | TLE1+, STAT6-, SOX10-, S100- |
| Biphenotypic sinonasal sarcoma | PAX3+, S100+, SMA+, SOX10-, STAT6-, TLE1- |
| Malignant peripheral nerve sheath tumor | SOX10+, S100+, STAT6-, TLE1-, INI1- (epithelioid type), h3k27me3- |
| Melanoma | SOX10+, S100+, STAT6-, TLE1- |