Table 2.

Respective critical values (P) and hazard ratios (HR) calculated via univariate cox proportional hazards regression analysis presented with presented with 95% Confidence Intervals (CI)

Factor	P	HR	95% CI
Male	0.428	1.59	0.50–5.02
Age (cont.)	0.924	1.01	0.96–1.04
Age ≥ 55	0.966	1.04	0.33–3.19
Rate of growth	0.904	0.94	0.33–2.57
Duration of symptoms	0.534	1.01	0.98–1.05
Pain	0.151	0.41	0.08–2.03
Tumor size (cont.)	0.151	1.21	0.94–1.54
Size < 4.9 cm	0.39	0.38	0.11–1.04
Size 5.0–9.9 cm	0.967	0.76	0.41–1.89
Size ≥ 10 cm	0.955	1.34	0.86–1.98
Mitotic activity (cont.)	0.354	1.04	0.96–1.12
Mitotic activity ≥ 4/10 hpf	0.291	0.40	0.07–2.19
Positive margins	< 0.001	0.069	0.02–0.27
Atypia, hemorrhage, or necrosis	0.088	0.36	0.07–1.26
Local invasion	0.079	0.34	0.08–1.15

Bold values indicate statistical significance

cont. continuously tested variable, hpf high powered field