Table 2.
Immunohistochemical profile of the glandular component of SMARCB1-deficient sinonasal adenocarcinomas
| Case | SMARCB1 | CK7 | CK20 | CDX2 | p40 | S100 | AFP | Glypican-3 | PLAP | SALL4 | HepPar-1 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Lost | F+ | – | – | – | – | – | + | F+ | + | – |
| 2 | Lost | F+ | – | – | – | – | – | – | – | – | – |
| 3 | Lost | + | – | – | – | – | ND | ND | ND | ND | ND |
| 4 | Lost | – | – | – | – | – | F+ | + | ND | + | – |
| 5 | Lost | + | + | – | ND | – | – | F+ | – | + | – |
| 6 | Lost | + | – | – | – | – | – | F+ | – | – | – |
| 7 | Lost | + | – | – | ND | ND | – | F+ | – | – | – |
| 8 | Lost | + | F+ | – | – | – | – | F+ | – | – | + |
| 9 | Lost | F+ | – | + | F+ | – | – | F+ | – | F+ | – |
| 10 | Lost | – | – | F+ | – | – | – | + | – | + | F+ |
| 11 | Lost | + | – | F+ | F+ | – | – | + | – | – | + |
| 12 | Lost | + | F+ | ND | F+ | – | ND | ND | ND | ND | ND |
ND not done, F+ focally positive